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, disorders of falling asleep). Take trazodone after a meal or a snack. Initial dose: 150 mg orally per day in divided doses; this may be increased by 50 mg orally per day every 3 to 4 days. IsHak is with the Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, California, and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California. Find out how trazodone treats depression and anxiety and how to take it. Trazodone can make you feel sleepy. PMCID: PMC5842888 There was no significant difference in trazodone use between the patients taking SSRIs or bupropion. Trazodone hydrochloride tablets are indicated for the treatment of major depressive disorder (MDD) in adults. Your doctor may occasionally change your dose. Maximum dose: Inpatients: 600 mg/day. Other off-label uses include the treatment of bulimia, benzodiazepine/alcohol dependence, fibromyalgia, central nervous system degenerative diseases (behavioral disorders in dementia and other organic. It can take 1 to 2 weeks before trazodone starts to work, but it may be 4 to 6 weeks before you feel the full benefit. It is, however, very effective in the treatment of sleep-maintenance insomnia, especially in patients with comorbid mental disorders or patients treated with activating antidepressants.. It may take up to 2 weeks before your symptoms improve Trazodone comes as tablets, capsules and liquid that you swallow. About trazodone Who can and cannot take it How and when to take it Side effects Pregnancy, breastfeeding and fertility Taking trazodone with other medicines and herbal supplements Common questions Related conditions Clinical depression. In this low-dose range, trazodone is thought to help encourage sleep while limiting the risk of daytime sleepiness. It is, however, very effective in the treatment of sleep-maintenance insomnia, especially. However, studies show lower dosages of trazodone are effective and may cause less daytime sleepiness and fewer side. Trazodone Dosage and Administration Dose Selection An initial dose of 150 mg/day in divided doses is suggested How should I take trazodone? It's only available on prescription. The percent of patients that received an SSRI, bupropion, or a TCA in combination with trazodone was 27%, 23%, and 13%, respectively. Follow all directions on your prescription label and read all medication guides or instruction sheets. Comments: Patients should be screened for a personal/family history of bipolar disorder, mania, or hypomania prior to initiating treatment Dr. For this indication it needs to be administered earlier than hypnotics, at least 1 hour before bedtime. 7% of patients received trazodone concomitantly with a primary antidepressant Insomnia is the most frequent reason for prescription of trazodone. Comments: Patients should be screened for a personal/family history of bipolar disorder, mania, or hypomania prior to initiating treatment Trazodone Brand name: Molipaxin. 7% of patients received trazodone concomitantly with a primary antidepressant In the treatment of insomnia, trazodone is less effective than hypnotics in the treatment of sleep onset insomnia (i. It has also been proven useful in the treatment of anxiety disorders. Doctors usually prescribe trazodone when other antidepressants have not worked or have caused side effects. Take trazodone exactly as prescribed by your doctor. The dosage should be initiated at a low-dose and increased gradually, noting the clinical response and any evidence of intolerance For sleep problems, doctors typically prescribe low doses of trazodone, between 25 and 100 milligrams (mg). As a treatment for depression, higher doses of trazodone (150-600 mg) are needed Dr. 1 Dose Selection An initial dose of 150 mg/day in divided doses is suggested.